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Proton Dipolar Recoupling in Resin-Bound Peptides under High-Resolution Magic Angle Spinning

✍ Scribed by Jésus Raya; Alberto Bianco; Julien Furrer; Jean-Paul Briand; Martial Piotto; Karim Elbayed

Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
594 KB
Volume
157
Category
Article
ISSN
1090-7807

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✦ Synopsis

Rotational resonance and radiofrequency-driven dipolar recoupling (RFDR) experiments have been used to recover the weak proton dipolar interaction present in peptides bound to swollen resins spun at the magic angle. The intensity of the correlation peaks obtained using these sequences is shown to be significantly stronger than the one obtained using the classical NOESY experiment. In addition, it is found that during the relatively long mixing times required to transfer magnetization in such soft materials, the RFDR sequence also achieves magnetization transfer via the scalar J-coupling.

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