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Proto-oncogene expression in germ cell development

✍ Scribed by Friedrich Propst; Michael P. Rosenberg; George F. Vande Woude

Book ID
113288654
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
575 KB
Volume
4
Category
Article
ISSN
0168-9525

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## Abstract Proto‐oncogene products may be multi‐functional proteins with various roles in cell differentiation as well as cell proliferation. The molecular biology of the gene products of three well characterized proto‐oncogenes (__c‐fos, c‐myc__ and __c‐src__) are described, and the roles of thre

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The expression of the protein products and mRNA of c-fos, c-myc, p53, and c-rafwas examined in normal renal tissues and biopsy specimens from 73 patients with various glomerular diseases. Immunofluorescent staining showed that there were cell nuclei stained for C-FOS, c-Myc, and p53, and cytoplasm p