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Proteostasis impairment in protein-misfolding and -aggregation diseases

✍ Scribed by Hipp, Mark S.; Park, Sae-Hun; Hartl, F. Ulrich

Book ID: 124149533
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 627 KB
Volume: 24
Category: Article
ISSN: 0962-8924
DOI: 10.1016/j.tcb.2014.05.003

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## Abstract The cellular surveillance systems guarantee proper removal of altered components from inside cells. Alterations of these systems in neurons have been proposed to be involved in the pathogenesis of different neurodegenerative disorders. In this review, we comment on the advances in our c