Regulation of HMG-CoA reductase expressi
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Valentina Pallottini; Barbara Guantario; Chiara Martini; Pierangela Totta; Irene
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Article
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2008
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John Wiley and Sons
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English
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## Abstract The ability to maintain O~2~ homeostasis is essential to the survival of all invertebrate and vertebrate species. The transcriptional factor, hypoxia inducible factor 1 (HIFโ1), is the principal regulator of oxygen homeostasis. Under hypoxic condition HIFโ1 induces the transcription of