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Proteomics analysis of MPP+-induced apoptosis in SH-SY5Y cells

โœ Scribed by Hongrong Xie; Ming Chang; Xinyu Hu; Danping Wang; Mingxiu Tian; Guoyi Li; Huiyi Jiang; Ying Wang; Zhong Dong; Yuhua Zhang; Linsen Hu


Book ID
106268962
Publisher
Springer Milan
Year
2010
Tongue
English
Weight
492 KB
Volume
32
Category
Article
ISSN
1590-1874

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A genetic defect in complex I of the mitochondrial electron transport chain (ETC) is implicated in the etiology of Parkinson's disease (PD), and has been studied in cybrid mitochondrial transgene cells based on the SH-SY5Y neuroblastoma. We sought to characterize further the mechanisms and time cour