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Proteomic analysis of mitochondria-to-nucleus retrograde response in human cancer cells

✍ Scribed by M. Kulawiec; H. Arnouk; M. Desouki; L. Kazim; I. Still; K. Singh

Book ID
116751553
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
55 KB
Volume
6
Category
Article
ISSN
1567-7249

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## Abstract In order to understand the molecular mechanisms of multidrug resistance (MDR) in ovarian cancer, we employed the proteomic approach of isobaric tags for relative and absolute quantification (iTRAQ), followed by LC‐MS/MS, using the cisplatin‐resistant COC1/DDP cell line and its parental