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Proteolysis in MHC Class II Antigen Presentation: Who's in Charge?

✍ Scribed by José A Villadangos; Hidde L Ploegh


Book ID
117722605
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
172 KB
Volume
12
Category
Article
ISSN
1074-7613

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The MHC class II molecules have been recognized as signaling receptors for more than a decade, and recent work has revealed the importance of their signaling for the immune response. Today, we know that the function of MHC class II molecules on antigen-presenting cells (APCs) is not limited to their