𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Proteoglycans/glycosaminoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses

Book ID
122886594
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
287 KB
Volume
11
Category
Article
ISSN
0197-4580

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## Abstract The extracellular accumulation of amyloid Ξ² proteins (AΞ²s) in neuritic plaques is one of the hallmarks of Alzheimer's disease (AD). The binding of AΞ²s to extracellular membranes (ECMs) is a critical step in developing AD. AΞ²s bind to many biomolecules, including lipids, proteins, and pr