Proteoglycan osmotic pressure and the collagen tension in normal, osteoarthritic human cartilage
β Scribed by Alice Maraudas
- Book ID
- 113214073
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 468 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0049-0172
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π SIMILAR VOLUMES
Proteases have been postulated to account for the progressive disappearance of matrix proteoglycans in osteoarthritic (OA) cartilage. The digestion of endogenous proteoglycans by neutral proteases in human OA cartilage homogenates has been measured and compared with that of normal age-matched contro
## Abstract The study was designed to determine the contents and distributions of the proteoglycans decorin and biglycan in adult human femoral condylar cartilage and whether these may change in osteoarthritis. New radioimmunoassays were established using peptides representing the aminoβterminal 21