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Proteins and Domains Vary in Their Tolerance of Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs)

โœ Scribed by Yates, Christopher M.; Sternberg, Michael J.E.


Book ID
121900318
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
590 KB
Volume
425
Category
Article
ISSN
0022-2836

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## Abstract Members of the human DNase I family, DNase Iโ€like 1 and 2 (DNases 1L1 and 1L2), with physiological role(s) other than those of DNase I, possess three and one nonโ€synonymous SNPs in the genes, respectively. However, only limited population data are available, and the effect of these SNPs