20S proteasomes and protein degradation
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Gad Asher; Nina Reuven; Yosef Shaul
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 128 KB
## Abstract The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin‐dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. Alternatively, certain p