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Protein-Tyrosine-Phosphatase Inhibition by Angiotensin-II in Rat Pheochromocytoma Cells Through Type-2 Receptor, at(2)

✍ Scribed by K. Takahasi; S. Bardhan; Y. Kambayashi; H. Shirai; T. Inagami

Book ID: 115574044
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 398 KB
Volume: 198
Category: Article
ISSN: 0006-291X
DOI: 10.1006/bbrc.1994.1009

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## Abstract Angiotensin II (Ang II) AT~2~ receptors are abundantly expressed in rat fetal tissues where they probably contribute to development. In the present study we examine the effects of Ang II type 2 receptor stimulation on SHP‐1 activation. Ang II (10^−7^ M) elicits a rapid and transient tyr