๐”– Bobbio Scriptorium
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Protein tyrosine kinases and cancer

โœ Scribed by Kathryn S Kolibaba; Brian J Druker

Book ID
114222944
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
730 KB
Volume
1333
Category
Article
ISSN
0304-419X

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Syk, a nonreceptor type of protein tyrosine kinase widely expressed in hematopoietic cells, is a candidate suppressor gene in human breast cancer. Reduced expression of Syk protein is correlated with poor prognosis, while its overexpression can reduce the malignant phenotype of breast cancer cells.