The erb type 1 tyrosine kinase receptors are important for mediating proliferation and differentiation, and aberrant activation may contribute to tumour development and progression. They comprise epidermal growth factor receptor (EGFR), c-erbB-2, c-erbB-3, and c-erbB-4. There are overlaps and differ
β¦ LIBER β¦
The ErbB/HER receptor protein-tyrosine kinases and cancer
β Scribed by Robert Roskoski Jr.
- Book ID
- 116288450
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 371 KB
- Volume
- 319
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
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## Abstract Recent experimental evidences begin to support the notion that the __proto__βoncogene HER2 (__erb__Bβ2) might unexpectedly function to modulate the adipogenic conversion of preadipocytes. Two opposing scenarios have been proposed, however, to explain the influence of HER2 on adipocyte d