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Protein tyrosine kinase inhibitor, genistein, enhances apoptosis and cell cycle arrest in K562 cells treated with γ-irradiation

✍ Scribed by Konstantinos T. Papazisis; Dimitra Zambouli; Ourania T. Kimoundri; Emmanuel S. Papadakis; Vasiliki Vala; George D. Geromichalos; Soultana Voyatzi; Dimitra Markala; Evangelia Destouni; Lazaros Boutis; Alexander H. Kortsaris

Book ID
117466667
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
400 KB
Volume
160
Category
Article
ISSN
0304-3835

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## Abstract ZD6474 is a vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. The present study was undertaken to investigate the direct antiproliferative effect of ZD6474 on human nasopharyngeal carcinoma (NPC) __in vitro__ and t