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The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells

✍ Scribed by Karsten Spiekermann; Florian Faber; Robert Voswinckel; Wolfgang Hiddemann


Book ID
114216855
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
300 KB
Volume
30
Category
Article
ISSN
0301-472X

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✍ Alessandro Sgambato; Andrea Camerini; Beatrice Faraglia; Raffaele Ardito; Gabrie πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 297 KB πŸ‘ 2 views

## Abstract The epidermal growth factor (EGF) plays a role in the development of prostate cancer, which becomes essential after androgen resistance has emerged. The EGF receptor (EGFR) is therefore a potential target for anticancer therapy. We evaluated the effects of ZD1839 (β€˜Iressa’), an orally a