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Protein tyrosine kinase activity as a prognostic parameter in breast cancer, a pilot study

✍ Scribed by M. Bolla; B. Rostaing-Puissant; M. Chedin; C. Souvignet; J. Marron-Charriere; M. Colonna; E. Berland; E. M. Chambaz

Book ID
104873633
Publisher
Springer US
Year
1993
Tongue
English
Weight
415 KB
Volume
26
Category
Article
ISSN
0167-6806

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Prognostic value of cytosolic thymidine
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Thymidine kinase (TK) is involved in DNA synthesis by the salvage pathway. In this study, thymidine kinase (TK) was determined in routinely prepared cytosols of primary tumors from 290 breast-cancer patients. Enzyme activity was measured using a radioenzymatic method optimized for detection of the f