Protein Structure and Denaturation.
β Scribed by RIMINGTON, CLAUDE
- Book ID
- 109495447
- Publisher
- Nature Publishing Group
- Year
- 1931
- Tongue
- English
- Weight
- 285 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/127440b0
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We studied the thermal denaturation of eglin c by using CD spectropolarimetry and differential scanning calorimetry (DSC). At low protein concentrations, denaturation is consistent with the classical two-state model. At concentrations greater than several hundred M, however, the calorimetric enthalp
## Abstract Virtually all studies of the proteinβfolding reaction add either heat, acid, or a chemical denaturant to an aqueous protein solution in order to perturb the protein structure. When chemical denaturants are used, very high concentrations are usually necessary to observe any change in pro