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Protein Sequence Randomization: Efficient Estimation of Protein Stability Using Knowledge-based Potentials

โœ Scribed by Markus Wiederstein; Manfred J. Sippl


Book ID
116661815
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
527 KB
Volume
345
Category
Article
ISSN
0022-2836

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Exploring Protein Sequence Space Using K
โœ ADERONKE BABAJIDE; ROBERT FARBER; IVO L. HOFACKER; JEFF INMAN; ALAN S. LAPEDES; ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 506 KB

Knowledge-based potentials can be used to decide whether an amino acid sequence is likely to fold into a prescribed native protein structure. We use this idea to survey the se-quence}structure relations in protein space. In particular, we test the following two propositions which were found to be im