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Protein Restriction Without Strong Caloric Restriction Decreases Mitochondrial Oxygen Radical Production and Oxidative DNA Damage in Rat Liver

✍ Scribed by Alberto Sanz; Pilar Caro; Gustavo Barja

Publisher
Springer US
Year
2004
Tongue
English
Weight
113 KB
Volume
36
Category
Article
ISSN
0145-479X

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## Abstract In the present study, the question if medium‐term (4 months) caloric restriction (40%) decreases mitochondrial H~2~O~2~ production and oxidative DNA damage was investigated. Caloric restriction (CR) is the only experimental manipulation that increases maximum life span. Previous long‐te