Protein-Protein Interactions

✍ Scribed by Michael D. Wendt (auth.), Michael D. Wendt (eds.)

Publisher: Springer-Verlag Berlin Heidelberg
Year: 2012
Tongue: English
Leaves: 281
Series: Topics in Medicinal Chemistry 8
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Michael D. Wendt
Protein-Protein Interactions as Drug Targets

Shaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev Kumar
Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics

Kurt Deshayes , Jeremy Murray , Domagoj Vucic
The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer

John F. Kadow , David R. Langley , Nicholas A. Meanwell , Michael A. Walker , Kap-Sun Yeung , Richard Pracitto
Protein-Protein Interaction Targets to Inhibit HIV-1 Infection

Nicholas A. Meanwell , David R. Langley
Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion – a Focus on Respiratory Syncytial Virus

Andrew B. Mahon , Stephen E. Miller , Stephen T. Joy , Paramjit S. Arora
Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces

Michael D. Wendt
The Discovery of Navitoclax, a Bcl-2 Family Inhibitor

✦ Table of Contents

Front Matter....Pages i-xviii
Protein-Protein Interactions as Drug Targets....Pages 1-55
Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics....Pages 57-79
The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer....Pages 81-103
Protein-Protein Interaction Targets to Inhibit HIV-1 Infection....Pages 105-165
Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion: A Focus on Respiratory Syncytial Virus....Pages 167-196
Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces....Pages 197-230
The Discovery of Navitoclax, a Bcl-2 Family Inhibitor....Pages 231-258
Back Matter....Pages 259-261

✦ Subjects

Chemistry/Food Science, general

📜 SIMILAR VOLUMES

Proteomics and Protein-Protein Interacti

📁 Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design (Protein Reviews)

✍ Gabriel Waksman 📂 Library 📅 2005 🏛 Springer 🌐 English

The rapidly evolving field of protein science has now come to realize the ubiquity and importance of protein-protein interactions. It had been known for some time that proteins may interact with each other to form functional complexes, but it was thought to be the property of only a handful of key p

Proteomics and Protein-Protein Interacti

📁 Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design

✍ Gabriel Waksman, Clare Sansom (auth.), Gabriel Waksman (eds.) 📂 Library 📅 2005 🏛 Springer US 🌐 English

Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street Lond

Protein-Protein Interactions

📁 Protein-Protein Interactions

✍ R. Jaenicke (auth.), Professor Dr. R. Jaenicke, Professor Dr. E. Helmreich (eds. 📂 Library 📅 1972 🏛 Springer-Verlag Berlin Heidelberg 🌐 English

Protein-Protein Interactions

📁 Protein-Protein Interactions

✍ Michael D. Wendt (auth.), Michael D. Wendt (eds.) 📂 Library 📅 2012 🏛 Springer-Verlag Berlin Heidelberg 🌐 English

Michael D. Wendt Protein-Protein Interactions as Drug TargetsShaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev Kumar Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer TherapeuticsKurt Deshayes , Jeremy Murray , Domagoj Vuci

Protein, Volume 2 (Proteins)

📁 Protein, Volume 2 (Proteins)

✍ G. Allen 📂 Library 📅 1999 🏛 Elsevier Science 🌐 English

In the first volume of this series, the structures of protein molecules were described, together with computational methods linking sequence data to folded structure and function. The determination of protein structure by nuclear magnetic resonance spectroscopy was also presented. Volume 2 begins by

Protein, Volume 2 (Proteins)

📁 Protein, Volume 2 (Proteins)

✍ G. Allen 📂 Library 📅 1999 🌐 English