In last decades, the basic, clinical, and translational research efforts have been directed to the identification of standard biomarkers associated with the degree of malignancy. There is an increasingly public health concern for earlier detection of cancer development at stages in which successful
Protein patterns as codes for tumor identification
✍ Scribed by David Irwin
- Book ID
- 102983504
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 568 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
✦ Synopsis
Particulate-fraction and soluble-fraction proteins from examples of breast carcinoma, Hodgkin's lympboma, and colon adenocarcinoma and their corresponding normal tissues were resolved on sodium dodecyl sulfate-polyacrylamide gels. The Coomassie blue-stained protein patterns were quantitated using a scanning densitometer and were reduced to simple threepart numerical codes. The codes were (a) specific for each tissue and (b) in the examples of lymphoma and colon adenocarcinoma, indicated a strong similarity between tumors and their respective normal tissues.
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