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Protein oxidation in male Syrian hamster kidney during estrogen-induced carcinogenesis

✍ Scribed by T Stefaniak; J Krajewski; J Kobiela; W Makarewicz; A Stanek; M Asano; R Kondo; T Wakabayashi; Z Gruca; M Woźniak

Book ID
118606170
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
333 KB
Volume
8
Category
Article
ISSN
0928-4680

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Microsomal preparations from hamster kidney, a target tissue for the carcinogenic action of stilbene-type and steroidal estrogens, catalyze the oxidative metabolism of diethylstilbestrol (DES). The formation of the major metabolite Z,Z-dienestrol and of reactive intermediates capable of protein bind