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Serum and tissue levels of estradiol during estrogen-induced renal tumorigenesis in the Syrian hamster

✍ Scribed by Li, Sara Antonia; Xue, Yan; Xie, Qiu; Li, Christopher I.; Li, Jonathan J.

Book ID
122846435
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
425 KB
Volume
48
Category
Article
ISSN
0960-0760

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To examine a direct involvement of genotoxic effects of estrogens in the initiation of hormonal carcinogenesis, the abilities of 17beta-estradiol (E2) and 8 of its metabolites to induce cellular transformation and genetic effects were studied using the Syrian hamster embryo (SHE) cell model. Treatme