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Protein kinase Cδ and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-κB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro

✍ Scribed by Kunal H. Bhatt; Rajeev Kumar Pandey; Yogesh Dahiya; Ajit Sodhi

Book ID: 116757600
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 965 KB
Volume: 47
Category: Article
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2009.10.029

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## Abstract Expression of inducible nitric oxide synthase (iNOS), which leads to the production of nitric oxide (NO), is stimulated by proinflammatory cytokines such as interleukin‐1β (IL‐1β) and tumor necrosis factor‐α (TNF‐α). Here we report on the roles of nuclear factor‐κB (NF‐κB) and mitogen‐a