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Protein kinase C α modulates growth and differentiation in Caco-2 cells

✍ Scribed by Clara Abraham; Beth Scaglione–Sewell; Susan F. Skarosi; Wenying Qin; Marc Bissonnette; Thomas A. Brasitus

Book ID
118520483
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
219 KB
Volume
114
Category
Article
ISSN
0016-5085

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Modulation of human Caco-2 intestinal epithelial cell phenotype by protein kinase C inhibitors
✍ Marc D. Basson; Fu Hong 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 435 KB

## Abstract Protein kinase C (PKC) isoforms are altered in colon tumors and upon exposure of intestinal mucosa to nutrients. We evaluated the effects of the PKC inhibitors staurosporine and calphostin C on human Caco‐2 intestinal epithelial proliferation, motility, and differentiation. Motility was