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Alterations in expression of protein kinase C-α in CACO-2 cells result in changes in cellular proliferation

✍ Scribed by B.A. Scaglione-Sewell; C. Abraham; N.O. Davidson; B. Davis; M. Bissonnette; T.A. Brasitus

Book ID: 118880140
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 164 KB
Volume: 108
Category: Article
ISSN: 0016-5085
DOI: 10.1016/0016-5085(95)26450-7

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Phorbol 12-myristate 13-acetate (PMA) has been shown to stimulate DNA synthesis and cell proliferation in a population of glial cells isolated from newborn rat brain. The non-tumor promoter 4a-phorbol l2,13-didecanoate (4a-PDD), on the other hand, was without an effect. The cultures treated with PMA