Protein kinase C co-expression and the effects of halothane on rat skeletal muscle sodium channels
โ Scribed by J Paul Mounsey; Manoj K Patel; Dilaawar Mistry; J Edward John; J Randall Moorman
- Book ID
- 110004616
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 245 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0007-1188
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๐ SIMILAR VOLUMES
The membrane electrical parameters and component conductances of rat extensor digitorum longus muscle fibres were studied in vitro at 30 ~ with standard two microelectrode square pulse cable analysis in the presence of protein kinase C (PKC) activators and inhibitors. The PKC activator, 4-[3-phorbol
## Abstract Myotonic muscular dystrophy (DM) is characterized by abnormal skeletal muscle Na channel gating and reduced levels of myotonic dystrophy protein kinase (DMPK). Electrophysiological measurements show that mice deficient in __Dmpk__ have reduced Na currents in muscle. We now find that the