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Protein Folding || Initial Studies of the Equilibrium Folding Pathway of Staphylococcal Nuclease

✍ Scribed by Yi Wang, Andrei T. Alexandrescu and David Shortle


Book ID
123646716
Publisher
The Royal Society
Year
1995
Tongue
English
Weight
878 KB
Volume
348
Category
Article
ISSN
0080-4622

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Predicting the equilibrium protein foldi
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The equilibrium folding pathway of staphylococcal nuclease (SNase) has been approximated using a statistical thermodynamic formalism that utilizes the highresolution structure of the native state as a template to generate a large ensemble of partially folded states. Close to 400,000 different states