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Partially Folded States of Staphylococcal Nuclease Highlight the Conserved Structural Hierarchy of OB-Fold Proteins†

✍ Scribed by Watson, Emma; Matousek, William M.; Irimies, Evelyn L.; Alexandrescu, Andrei T.


Book ID
115501928
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
547 KB
Volume
46
Category
Article
ISSN
0006-2960

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Predicting the equilibrium protein foldi
✍ Vincent J. Hilser; Ernesto Freire 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

The equilibrium folding pathway of staphylococcal nuclease (SNase) has been approximated using a statistical thermodynamic formalism that utilizes the highresolution structure of the native state as a template to generate a large ensemble of partially folded states. Close to 400,000 different states