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Protein-DNA Interactions Studies using Magnetic Tweezers

✍ Scribed by Wiggin, Matthew J.; Dekker, Nynke

Book ID: 122149440
Publisher: Biophysical Society
Year: 2010
Tongue: English
Weight: 47 KB
Volume: 98
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2009.12.3229

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## Abstract We present the first results obtained with a new instrument designed and built to study DNA–protein interactions at the single molecule level. This microscope combines optical tweezers with scanning probe microscopy and allows us to locate DNA‐binding proteins on a single suspended DNA