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Using DNA Handles in Optical Tweezers Studies of Protein Mechanics

✍ Scribed by Rezaei, Naghmeh; Miao, Megan; Downing, Benjamin P.B.; Keeley, Fred W.; Forde, Nancy R.

Book ID
122586700
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
36 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract The last decade has seen rapid development in single molecule manipulation of RNA and DNA. Measuring the response force for a particular manipulation has allowed the free energies of various nucleic acid structures and configurations to be determined. Optical tweezers represent a class