Protein Disorder Prediction: Implications for Structural Proteomics
โ Scribed by Rune Linding; Lars Juhl Jensen; Francesca Diella; Peer Bork; Toby J Gibson; Robert B Russell
- Book ID
- 113918114
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 219 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0969-2126
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One of the key steps of structural genomics and proteomics is high-throughput expression of many target proteins. Gene cloning, especially by ligation-independent cloning techniques, and recombinant protein expression using microbial hosts such as Escherichia coli and the yeast Pichia pastoris are w
## Background Determining the complete repertoire of protein structures for all soluble, globular proteins in a single organism has been one of the major goals of several structural genomics projects in recent years. ## Results We report that this goal has nearly been reached for several "minimal