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Utilization of protein intrinsic disorder knowledge in structural proteomics

โœ Scribed by Oldfield, Christopher J.; Xue, Bin; Van, Ya-Yue; Ulrich, Eldon L.; Markley, John L.; Dunker, A. Keith; Uversky, Vladimir N.


Book ID
118137148
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
657 KB
Volume
1834
Category
Article
ISSN
1570-9639

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Fluorescence spectroscopy can be successfully used in studies of intrinsically disordered proteins (IDPs). IDPs are usually characterized by surface location of tryptophan residues with redshifted tryptophan fl uorescence spectra with maxima at 340 -353 nm. Such tryptophans are readily accessible to