## Abstract Deregulation of protein kinases is associated with numerous diseases, making them important targets for drug discovery. The majority of drugs target the catalytic site of these proteins, but due to the high level of similarity within the ATP binding sites of protein kinases, it is often
โฆ LIBER โฆ
Protein binding site analysis by means of structural interaction fingerprint patterns
โ Scribed by Stefan Mordalski; Tomasz Kosciolek; Kurt Kristiansen; Ingebrigt Sylte; Andrzej J. Bojarski
- Book ID
- 113496170
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 696 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Analysis of water patterns in protein ki
โ
Caterina Barillari; Anna L. Duncan; Isaac M. Westwood; Julian Blagg; Rob L. M. v
๐
Article
๐
2011
๐
John Wiley and Sons
๐
English
โ 478 KB
Sequence and structural analysis of bind
โ
M. Michael Gromiha; Kiyonobu Yokota; Kazuhiko Fukui
๐
Article
๐
2010
๐
Elsevier Science
๐
English
โ 587 KB
Statistical analysis of structural chara
โ
Michael Kirberger; Xue Wang; Hai Deng; Wei Yang; Guantao Chen; Jenny J. Yang
๐
Article
๐
2008
๐
John Wiley and Sons
๐
English
โ 659 KB
Structural analysis of cationโฯ interact
โ
M.Michael Gromiha; C Santhosh; Shandar Ahmad
๐
Article
๐
2004
๐
Elsevier Science
๐
English
โ 113 KB
Difference in the energies of interactio
โ
Pinak Chakrabarti; Sourav Pal
๐
Article
๐
1993
๐
Elsevier Science
๐
English
โ 217 KB
Biomolecular associations are governed by energetics that influence the stable or the transient nature of various bindings. Ab initio MO calculations on model systems representing a metal ion-carboxylate-water triad in proteins have been performed. Depending on the structural or catalytic role of th
Duality of substrateโbinding site intera
โ
Wolf R. Vieth; Andrea Soddu
๐
Article
๐
1980
๐
Elsevier Science
โ 311 KB