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Protein binding and hepatic clearance: Studies with tolbutamide, a drug of low intrinsic clearance, in the isolated perfused rat liver preparation

✍ Scribed by William L. Schary; Malcolm Rowland


Book ID
112473447
Publisher
Springer
Year
1983
Tongue
English
Weight
879 KB
Volume
11
Category
Article
ISSN
1573-8744

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✍ Jean-Marie Colet; Luce Vander Elst; Robert N. Muller πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 681 KB

## Abstract This spectroscopic study compares the mechanisms of the hepatic uptake of manganese chloride (MnCl~2~) and manganese dipyridoxyl diphosphate (MnDPDP). Alterations of the phosphorus‐31 (^31^P)‐NMR spectrum of the intracellular adenosine 5′‐triphosphate (ATP) are used to monitor the inter