Protein Adsorption onto Protein-Covered Silica Gels

✍ Scribed by Sven Oscarsson

• Book ID: 102970125
• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 506 KB
• Volume: 165
• Category: Article
• ISSN: 0021-9797
• DOI: 10.1006/jcis.1994.1244

✦ Synopsis

Porous silica beads have been modified with aminoalkyl and thioalkyl groups of different chain lengths. The modified silicas were covered with human (1 \mathrm{gG}) or human HSA. In order to investigate the influence of the underlying surface on the adsorbed protein layer, the adsorption onto and desorption and displacement of proteins from protein-covered surfaces were studied and compared with those for siliea surfaces not previously covered with protcin. 'The underlying surface exerted a great influence on the composition of the protein-covered surface. (1994 Academic Press, Inc.