Optimal stereoselectivities in the OsO4-catalyzed dihydroxylation of chiral yamino ¢x,~-unsaturated esters are achieved by the proper choice of the protective groups at nitrogen [t-butoxycarbonyl (Boc) versus dibenzyl] and the correct choice of the chiral ligand of the catalyst (AD-mix-c~ versus AD-
Protective group tuning in the stereoselective conversion of α-amino aldehydes into aminoalkyl epoxides
✍ Scribed by M.T. Reetz; J. Binder
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 251 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of anti-and syn-β-Amino Alcohols with Functionalized Allyl Groups. -Anti-and syn-amino alcohols can be prepared in high yields with good to excellent diastereoselectivity. The amino alcohol (IV