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ChemInform Abstract: Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of anti- and syn-β- Amino Alcohols with Functionalized Allyl Groups.

✍ Scribed by S. HANESSIAN; H. PARK; R.-Y. YANG

Publisher: John Wiley and Sons
Year: 2010
Weight: 33 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199740100

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✦ Synopsis

Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution.

Stereoselective Synthesis of anti-and syn-β-Amino Alcohols with Functionalized Allyl Groups.

-Anti-and syn-amino alcohols can be prepared in high yields with good to excellent diastereoselectivity. The amino alcohol (IVa) can easily be converted into the lactone (V), a potent intermediate of hydroxyethylene dipeptide isosteres. -

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ChemInform Abstract: Zinc-Mediated Allyl

ChemInform Abstract: Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of Phe-Phe Hydroxyethylene Dipeptide Isosteres.

✍ S. HANESSIAN; H. PARK; R.-Y. YANG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB