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Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats

✍ Scribed by Basarslan, F.; Yilmaz, N.; Ates, S.; Ozgur, T.; Tutanc, M.; Motor, V.; Arica, V.; Yilmaz, C.; Inci, M.; Buyukbas, S.

Book ID
121685504
Publisher
SAGE Publications
Year
2012
Tongue
English
Weight
413 KB
Volume
31
Category
Article
ISSN
0960-3271

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Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r