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Protective effects of MK-801 on manganese-induced glutamate metabolism disorder in rat striatum

โœ Scribed by Bin Xu; Zhao-Fa Xu; Yu Deng

Book ID
113608126
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
677 KB
Volume
62
Category
Article
ISSN
0940-2993

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The effects of glutamate and its agonists and antagonists on the swelling of primary astrocytes were studied. Glutamate (Glu), aspartate (Asp), homocysteate (HCA), and quisqualate (Quis) at 1 mM concentration caused a significant increase in astrocytic swelling as measured by the 3-0-methyl-['4C]-gl