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Protective Effect of Lycopene on Oxidative Stress and Cognitive Decline in Rotenone Induced Model of Parkinson’s Disease

✍ Scribed by Harpreet Kaur; Shaveta Chauhan; Rajat Sandhir

Publisher
Springer
Year
2011
Tongue
English
Weight
274 KB
Volume
36
Category
Article
ISSN
0364-3190

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## Abstract A typical feature of Parkinson's disease is the progressive loss of dopaminergic neurons in the substantia nigra, in which inhibition of mitochondrial complex I activity may play an important role. Rotenone or 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) inhibit the mitochondrial