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Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum

✍ Scribed by Vizuete, M.L.; Steffen, V.; Ayala, A.; Cano, J.; Machado, A.

Book ID
122882374
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
326 KB
Volume
152
Category
Article
ISSN
0304-3940

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We have studied the effect of a semichronic and acute treatment of phenobarbital on in vivo 1-methyl-4-phenylpyridinium ion- (MPP+)-induced neurotoxicity. A group of rats were intraperitoneally injected for 12 days with phenobarbital (80 mg/Kg of body weight, semichronic treatment) in order to induc