Protective effect of 2,3-butanedione monoxime on the myocardial ischemia in rats
โ Scribed by E. L. Levitskaya; A. N. Khatkevich; V. I. Veksler; V. I. Kapel'ko
- Publisher
- Springer US
- Year
- 1993
- Tongue
- English
- Weight
- 330 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0007-4888
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2,3-butanedione 2-monoxime (BDM, 3-30 mM) decreased twitch force of intact ventricular trabeculae isolated from 19-day embryonic chick hearts in a dose-dependent manner. The responses to BDM were rapid and reversible. In an attempt to determine the cellular basis for the inhibitory effect of BDM, ex
2,3-Butanedione monoxime and atropine alone or in combination were evaluated for their ability to alleviate the toxicity and to reverse the biochemical changes induced by dichlorvos in the blood of buffalo calves. Treatment with 2,3-butanedione monoxime plus atropine 30 min after oral administration