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Protective action of antioxidants on development of experimental allergic encephalomyelitis in guinea pigs

✍ Scribed by G. N. Kryzhanovskii; G. A. Vilkov; E. M. Stepanenko

Publisher: Springer US
Year: 1984
Tongue: English
Weight: 331 KB
Volume: 98
Category: Article
ISSN: 0007-4888
DOI: 10.1007/bf00800003

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## Abstract The highly encephalitogenic guinea pig peptide 68‐88 has been used to develop an effective and reproducible model of protection in the Lewis rat. Doses as low as 0.1 nmol of peptide protected 70% of rats when injected intraperitoneally six and four weeks prior to challenge with 0.05 nmo