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Protection of PC12 cells by glutathione peroxidase in L-DOPA induced cytotoxicity

✍ Scribed by Jeong Sook Kim-Han; Albert Y. Sun

Book ID
114276933
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
270 KB
Volume
25
Category
Article
ISSN
0891-5849

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## Abstract The effects of scoparone on dopamine biosynthesis and L‐DOPA‐induced cytotoxicity in PC12 cells were investigated. PC12 cells treated with scoparone at concentrations of 100–200 ΞΌM showed a 128–136% increase in dopamine levels over the course of 24 hr. Scoparone significantly increased