𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Proteasome inhibitor–induced model of Parkinson's disease

✍ Scribed by Kevin St. P. McNaught; C. Warren Olanow

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
722 KB
Volume
60
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Proteasome inhibitor model of Parkinson'
Proteasome inhibitor model of Parkinson's disease in mice is confounded by neurotoxicity of the ethanol vehicle
✍ Anne M. Landau; Edouard Kouassi; Rosmarie Siegrist-Johnstone; Julie Desbarats 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB

## Abstract Defects in the ubiquitin‐proteasome system have been implicated in Parkinson's Disease (PD). Recently, a rat model of PD was developed using a synthetic proteasome inhibitor (PSI), (Z‐lle‐Glu(O__t__Bu)‐Ala‐Leu‐al). We attempted to transfer this model to mouse studies, where genetics can

Ubiquitin–proteasome system and Parkinso
Ubiquitin–proteasome system and Parkinson's disease
✍ C. Warren Olanow; Kevin St. P. McNaught 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

## Abstract Increasing genetic, pathological, and experimental evidence suggest that neurodegeneration in both familial and sporadic forms of Parkinson's disease (PD) may be related to a defect in the capacity of the ubiquitin–proteasome system (UPS) to clear unwanted proteins, resulting in protein

Models of Parkinson's disease
Models of Parkinson's disease
✍ Michael Orth; Sarah J. Tabrizi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB

## Abstract Parkinson's disease (PD) is a heterogenous disease likely to be caused by more than one specific aetiological factor. In rare familial cases of PD with similar clinical features to the idiopathic form of the disease, the underlying genetic cause has been identified. These PD‐associated