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Proteasome and peptidase function in MHC-class-I-mediated antigen presentation

✍ Scribed by Peter-Michael Kloetzel; Ferry Ossendorp


Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
482 KB
Volume
16
Category
Article
ISSN
0952-7915

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## Abstract SSX2 is a member of the family of cancer/testis antigens. The SSX2 derived peptide SSX2~103–111~ has been shown to be presented to cytotoxic T‐lymphocytes (CTL) by Major‐Histocompatibility (MHC) Class‐I complexes after endogenous processing, more precisely by the allele HLA‐A\*0201. The