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Proteases in Fas-mediated apoptosis

✍ Scribed by Boris Zhivotovsky; David H. Burgess; Jörg Schlegel; M. Isabella Pörn; Daina Vanags; Sten Orrenius


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
156 KB
Volume
64
Category
Article
ISSN
0730-2312

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✦ Synopsis


Involvement of a unique family of cysteine proteases in the multistep apoptotic process has been documented. Cloning of several mammalian genes identifies some components of this cellular response. However, it is currently unclear which protease plays a role as a signal and/or effector of apoptosis. We summarize contributions to the data concerning proteases in Fas-mediated apoptosis.


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