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Protease-activated receptors-1 and -2 can mediate endothelial barrier protection: role in factor Xa signaling

✍ Scribed by C. FEISTRITZER; R. LENTA; M. RIEWALD


Book ID
109149230
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
216 KB
Volume
3
Category
Article
ISSN
1538-7933

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## Abstract Factor Xa (FXa) elicits intracellular signaling responses through the activation of protease‐activated receptor 2 (PAR2) and possibly also through PAR1 in endothelial cells. In this study, we investigated FXa signaling in endothelial cells when the protease was either in free form or as